| 利用动脉血液的时变差分光谱实现血氧饱和度的测量 |
| 投稿时间：2009-03-23 修订日期：2009-04-01 点此下载全文 |
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| 中文摘要: 血氧饱和度的无创检测已在临床医学中得到广泛应用。目前的测量方法主要基于人手指的双波长光度分析原理，存在测量重复性差、检测速率低和误差大等缺陷；由于完全忽略光散射的影响，理论上有不合理性。为了改进现有技术，分析了光散射对手指组织吸光度的影响，并根据动脉血液在红外及近红外区域（600nm-1000nm）吸光度的时变特性，引入时变差分光谱的概念；提出了利用时变差分光谱实现血氧饱和度测量的方法，并首次推导出包含光散射因子的血氧饱和度计算公式。与现有技术的对比表明，该测量方法具有测量准确、检测速率高、抗干扰性强和方便实现的特点；理论上更严谨、更科学。 |
| 中文关键词:时变差分光谱 光散射 血氧饱和度 动脉血液 无创检测 |
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| Measurement of Oxygenation Saturation Using Time-varying Differential Spectrum of Arterial Blood |
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| Abstract: Non-invasive measurement of oxygen saturation has been widely used in clinical medicine. The current measurement method is mainly based on the principle of dual-wavelength spectrophotometry analysis for the human finger. However, there are some flaws in which, such as poor measuring repeatability, low detecting rate, big error, etc. And it’s unreasonable in theory that the effect of light scattering is ignored totally. In order to improve the measurement technique, the influences of light scattering on finger tissues absorbance were analyzed, and, according to the time-varying property of arterial blood absorbance within red and near-infrared region (600nm-1000nm), the concept of time-varying differential spectrum was introduced. A novel measuring method based on time-varying differential spectrum was proposed, also, for the first time, a formula for calculating the oxygen saturation which contains light-scattering factor was derived. The comparison with the existing technique show that this method has better accuracy, higher detecting rate, stronger anti-interference, and easier realization; Meanwhile it’s more rigorous and more scientific in theory.
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| keywords:Time-varying differential spectrum, Light scattering, Oxygen saturation, Arterial blood, Non-invasive measurement |
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